[2.2]PHANEPHOS-ruthenium(II) complexes: Highly active asymmetric catalysts for the hydrogenation of β-ketoesters

Article abstract of DOI:10.1016/S0040-4039(98)00842-9

The application of the planar chiral [2.2]PHANEPHOS ligand in the Ru(II)-catalyzed asymmetric hydrogenation of β-ketoesters gave up to 96% ee involving a practical and reproducible procedure using the defined and readily prepared [2.2]PHANEPHOS-Ru(II)bis(trifluoroacetate) salt in the presence of a halide source.