Tetrahedron Letters p. 8019 - 8022 (1994)
Update date:2022-08-11
Topics:
Frigerio, Marco
Santagostino, Marco
o-Iodoxybenzoic acid (IBX) smoothly oxidizes primary and secondary alcohols to aldehydes and ketones, respectively. 1,2-Diols are converted to α-ketols or α-diketones without any oxidative cleavage of the glycol C-C bond.IBX oxidations are easily conducted in DMSO solution at room temperature, with yields ranging from good to quantitative.
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