2-Phenylpyrroles as Conformationally Restricted Benzamide Analogues. A New Class of Potential Antipsychotics. 1.

DOI: 10.1021/jm00394a028

Source and publish data:

Journal of Medicinal Chemistry p. 2099 - 2104 (1987)

Update date:2022-08-16

Topics:

Authors:

Wijngaarden, Ineke van

Kruse, Chris G.

Hes, Roelof van

Heyden, Jan A. M.van der

Tulp, Martin Th. M.

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Article abstract of DOI:10.1021/jm00394a028

2-Phenylpyrroles were synthesized as conformationally restricted analogues of the substituted benzamide sultopride and the butyrophenones haloperidol and fluanisone.Dopamine antagonistic activity is maintained if the 2-phenylpyrrole side chain is linked t

Full text of DOI:10.1021/jm00394a028

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