β-Cyclodextrin-Epichlorohydrin Copolymers as Efficient Catalysts in Phase-Transfer-Catalyzed Nucleophilic Substitution Reactions

Article abstract of DOI:10.1246/cl.1987.715

Copolymers of β-cyclodextrin (β-CD) with epichlorohydrin showed much higher phase-transfer catalytic activity than β-CD in liquid-liquid two-phase nucleophilic displacement reactions.The enhanced efficiency of the polymer catalysts was attributed to the cooperative effect of more than one β-CD group in polymers in bringing a substrate from an organic phase to an aqueous phase.