Synthetic Communications p. 2093 - 2102 (1997)
Update date:2022-08-17
Topics:
Blanton, James R.
A phase transfer reagent derived from PEG-sodium borohydride was developed which controlled both the activity and the amount of the reagent in the organic phase. Using this reagent under solid-liquid phase transfer conditions, it was found that aldehydes could be selectively reduced in the presence of ketones without concurrent reduction of the ketone group. The reactions were conducted at room temperature and were generally complete within two hours.
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