Hydrogen bonding of 1-cyclohexyluracil with acetylglycine N-methylamide

Article abstract of DOI:10.1016/0584-8539(84)80191-9

I.r. spectroscopy was used to determine the enthalpy of hydrogen bond complex formation of 1-cyclohexyluracil with acetylglycine N-methylamide, in chloroform solution.Enthalpy of association is found to be -5.4 Kcal/mole for the dimer of acetylglycine N-methylamide and -4.7 Kcal/mole for the mixed dimers of this dipeptide with 1-cyclohexyluracil.These thermodynamic parameters and the i.r. spectra of the solutions suggest that the structures of these dimers are cyclic.