Sonication-Induced Halogenative Decarboxylation of Thiohydroxamic Esters

Article abstract of DOI:10.1021/jo00287a023

The sonication of primary, secondary, and tertiary thiohydroxamic esters in CCl4 has led to their synthetic transformation to alkyl chlorides, bromides, or iodides.The high yields were comparable to the previous thermal-or photoinduced version of this same reaction.This radical reaction calls attention to the utility of ultrasound in production of trichloromethyl radical, which was concluded to initiate decomposition of the thiohydroxamic esters.