A mild and efficient method for converting alcohols and tetrahydropyranyl ethers to bromides with inversion of configuration

Article abstract of DOI:10.1016/S0040-4039(97)00232-3

Bromotriphenylphosphonium salt 2, generated by adding 2,4,4,6-tetrabromo-2,5-cyclohexamenone (1) to triphenylphosphine in CH₂Cl₂ or CH₂CN converted alcohols and tetrahydropyranyl ethers to the corresponding bromides in high yields.