Synthesis and renin inhibitory activity of angiotensinogen analogues having dehydrostatine, Leuψ[CH2S]Val, or Leuψ[CH2SO]Val at the P1-P1' cleavage site

DOI: 10.1021/jm00402a022

Source and publish data:

Journal of Medicinal Chemistry p. 1377 - 1382 (1988)

Update date:2022-08-17

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Authors:

Smith Smith

Saneii Saneii

Sawyer Sawyer

Pals Pals

Scahill Scahill

Kamdar Kamdar

Lawson Lawson

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Article abstract of DOI:10.1021/jm00402a022

The synthesis and in vitro renin inhibitory potencies of angiotensinogen (ANG) analogues having amide (CONH) bond replacements at P₁-P₁', the Leu-Val cleavage site, corresponding to Leuψ[CH₂S]Val, Leuψ[CH₂SO]Val

Full text of DOI:10.1021/jm00402a022

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