A straightforward synthesis of proclavaminic acid, a biosynthetic precursor of clavulanic acid

DOI: 10.1016/0957-4166(96)00282-0

Source and publish data:

Tetrahedron Asymmetry p. 2277 - 2286 (1996)

Update date:2022-08-11

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Authors:

Di Giovanni, Maria Cristina

Misiti, Domenico

Villani, Claudio

Zappia, Giovanni

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Article abstract of DOI:10.1016/0957-4166(96)00282-0

A stereocontrolled synthesis of (2S,3R)-5-amino-3-hydroxy-2-(2-oxoazetin-1-yl) pentanoic acid, proclavaminic acid 3, has been achieved via the homochiral 4,5-disubstituted oxazolidin-2-one 4.

Full text of DOI:10.1016/0957-4166(96)00282-0

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