Synthesis p. 584 - 586 (1987)
Update date:2022-08-30
Topics:
Barluenga, Jose
Fernandez-Simon, Jose L.
Concellon, Jose M.
Yus, Miguel
The in situ generated chloromethyl-lithium reacts at -78 deg C to -30 deg C with different acid chlorides (2:1 molar ratio) to afford, after lithiation with lithium powder, 1-substituted cyclopropanols.
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