Tetrahedron Letters p. 1351 - 1354 (1988)
Update date:2022-08-17
Topics:
Shrader, William D.
Celebuski, Joseph
Kline, Steven J.
Johnson, David
A new hexadentate chelator was synthesized by the functionalization of 8-hydroxyquinoline to its 2-carboxy-N-hydroxysuccinimidyl ester and a subsequent condensation with tris(2-aminoethyl)amine to give tris-N-(2-aminoethyl-<8-hydroxyquinoline-2-carboxamido>)amine.This molecule is a siderophore analog with a non-naturally occurring binding unit comprising a combination of both oxygen and nitrogen donor atoms.
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