Studies on the chemistry of the chiral nitronic acid and nitronic esters

Article abstract of DOI:10.1016/S0957-4166(97)00478-3

Some new chemistry of the chiral nitronic acid and nitronic esters is described. Conversions with retention of configuration are found among the chiral nitronic acid, oxime, nitronic esters and O-alkyloximes. α,β- Elimination reactions of nitronic esters are observed for the first time. Novel and enantiopure chiral bisheterocyclic compounds are obtained via highly diastereoselective 1,3-dipolar cycloaddition of the chiral nitronic esters with ethyl acrylate.