Tetrahedron p. 1431 - 1440 (1988)
Update date:2022-08-07
Topics: Ylides Nucleophilic Attack Structure-Activity Relationship (SAR) Carbonyl Addition Catalytic Activity
Sinisterra, J. V.
Marinas, J. M.
Riquelme, F.
Arias, M. S.
The reactivity of several products R1R2CH-X(1+), 1, (X=N,P,S), which can produce ylids by reaction with bases, has been tested using the activated barium hydroxide catalysts, C-200.Wittig-Horner, Wittig, Corey-Chaykovsky and Kroehnke type reactions have been analyzed.The pKa of 1, and the structure of active sites control the process.When 1 has a strong acid character, the process takes place - dissolving the solid - in homogeneous phase.When 1, has pKa values < 11, the process takes place in the strong basis sites of the solid (pKa > 11.7), that control the reaction mechanism and the reactivity of adsorbed ylids.
View MoreHangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Shanghai Goyic Pharmaceutical&Chemical Co,. Ltd
Contact:+86-021-60275964
Address:No. 528 ruiqing road
shandong lukang animal & plant drug trading co.,ltd.
Contact:15853765968
Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china
Refine Chemicals Science & Technology Technology Developing Co., Ltd.
Contact:+86-22-87899130
Address:No.12,west keyan road,Tianjin City
Suzhou Chiral Pharmaceuticals Co., Ltd.
Contact:86-0512-63197058
Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Doi:10.1016/j.tetlet.2010.12.107
(2011)Doi:10.1016/j.bmc.2010.09.073
(2010)Doi:10.1021/ol200531k
(2011)Doi:10.1021/ol200536h
(2011)Doi:10.1021/jm101027s
(2011)Doi:10.1134/S1070428017120028
(2017)