Piperonal as electrophile in the Baylis-Hillman reaction. A synthesis of hydroxy-β-piperonyl-γ-butyrolactone derivative

Article abstract of DOI:10.1016/S0040-4039(98)01927-3

Aromatic aldehydes are reluctant to serve as substrates for the Baylis- Hillman reaction at all under the relatively mild conditions. In our research, we have achieved that piperonal could be an useful substrate in this reaction, employing ultrasound tech