Organic Letters p. 6336 - 6339 (2017)
Update date:2022-07-29
Topics:
Ryzhakov, Dmytro
Jarret, Maxime
Guillot, Régis
Kouklovsky, Cyrille
Vincent, Guillaume
The dearomative introduction of trifluoromethyl and 1,1-difluoroethyl radicals, generated from their corresponding sulfinate salts, into the C2 position of indole derivatives allows the diastereoselective synthesis of three-dimensional 3,3-spirocyclic indolines over C-H functionalized indoles.
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