A NOVEL METHOD FOR THE SYNTHESIS OF β-LACTAMS BY MEANS OF PHASE TRANSFER SYSTEM

DOI: 10.1246/cl.1981.443

Source and publish data:

Chemistry Letters p. 443 - 444 (1981)

Update date:2022-08-12

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Authors:

Watanabe, Yutaka

Mukaiyama, Teruaki

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Article abstract of DOI:10.1246/cl.1981.443

The reaction of β-amino acids with methanesulfonyl chloride in a chloroform-water bilayer system in the presence of 15 molpercent of tetrabutylammonium hydrogen sulfate gives the corresponding β-lactams in good yields.

Full text of DOI:10.1246/cl.1981.443

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