Organic and Biomolecular Chemistry p. 747 - 751 (2015)
Update date:2022-08-11
Topics:
Zhan, Yang
Zhang, Xiao-Wei
Xiong, Ying
Li, Bo-Liang
Nan, Fa-Jun
A series of pyripyropene A-based compounds were designed and synthesized by opening the upper section of the A-ring, which significantly simplifies the structure and synthesis from commercially available starting materials. Representative compound (-)-3 exhibited potent activity against ACAT2 and greater selectivity for ACAT2 than for ACAT1.
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