Journal of Medicinal Chemistry p. 788 - 792 (1989)
Update date:2022-08-02
Topics:
Deutsch
Glinski
Hernandez
Haugwitz
Narayanan
Suffness
Zalkow
Taxol has shown good in vivo antitumor activity in a number of test systems. The formulation of taxol for antitumor testing has been difficult. Esterification at either C-2' or C-7 resulted in loss of in vitro tubulin assembly activity but not cytotoxicit
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