Selective Reductions. 52. Efficient Asymmetric Reduction of α-Acetylenic α'-Fluoroalkyl Ketones with Either B-Chlorodiisopinocampheylborane or B-Isopinocampheyl-9-borabicyclononane in High Enantiomeric Purity. The Influence of Fluoro Groups in Such

Article abstract of DOI:10.1016/0957-4166(94)80056-1

A systematic study of the asymmetric reduction of prochiral α-acetylenic α'-fluoroalkyl ketones with (-)-B-chlorodiisopinocampheylborane <(-)-DIP-Chloride, 1> and (-)-B-isopinocampheyl-9-borabicyclo<3.3.1>nonane (R-Alpine-Borane, 2) reveals that perfluoro