Solvent and Other Effects on the Stereoselectivity of Thioglycoside Glycosidations

Article abstract of DOI:10.1055/s-1997-5762

Iodonium-ion mediated glycosidation of thioglycosides in toluene/1,4-dioxane gives much higher α-selectivities than the use of conventional glycosylation solvents. Furthermore, it is shown that the iodonium-ion source, concentration and presence of molecu