
Chemistry of Heterocyclic Compounds p. 1262 - 1266 (1987)
Update date:2022-08-16
Topics:
Mandrugin, A. A.
Fedoseev, V. M.
Khomutov, S. M.
Rodyunin, A. A.
Leshchev, Yu. A.
We have demonstrated the basic possibility of cyclizing guanidinoalkanethiols of different structure to thiazolines and thiazines.The rate of reaction depends on the pH of the medium.The concentration of buffer and the addition of heavy water and α-D,L-alanine have virtually no effect on the rate of reaction.
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