A Facile Hydroxymethylation of Acetylene Derivatives with Paraformaldehyde by Use of an Electrogenerated Base (EG Base)

Article abstract of DOI:10.1246/cl.1988.1977

Electrolysis of a mixture of paraformaldehyde and terminal acetylene derivatives smoothly provided the corresponding hydroxymethylated compounds in high yields by passing less then 1 F/mol of electricity.Electroreduction of paraformaldehyde generated in e