Total deprotection of N,N'-bis(tert-butoxycarbonyl)guanidines using SnCl4

Article abstract of DOI:10.1016/S0040-4039(97)10148-4

The total deprotection of NdV'-bis-Boc guanidines using SnCl₄ proceeds smoothly in ethyl acetate at room temperature and leads to the easily isolable corresponding guanidinium chlorides.