A convenient synthesis of isothiazolo[5,4-b]indole (brassilexin) via a polyphosphoric acid initiated ring closure

DOI: 10.1055/s-1990-26834

Source and publish data:

Synthesis p. 214 - 215 (1990)

Update date:2022-08-17

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Authors:

Devys Devys

Barbier Barbier

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Article abstract of DOI:10.1055/s-1990-26834

Brassilexin (4), an antifungal compound previously isolated from Brassica juncea L. (Cruciferae), has been synthesized with an overall yield of 11% starting from 3-indolecarbaldehyde (1).

Full text of DOI:10.1055/s-1990-26834

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