Journal of the Chemical Society. Perkin transactions I p. 605 - 609 (1996)
Update date:2022-08-30
Topics:
Chambers, Richard D.
Skinner, Christopher J.
Hutchinson, John
Thomson, Julie
Direct fluorination of 4-fluorobenzoic acid, as a model substrate in a variety of reaction media, shows that 98% formic acid and concentrated sulfuric acid are excellent for promoting electrophilic fluorination. A high degree of fluorination may be achieved using concentrated sulfuric acid, showing that in this medium fluorine will act as a powerful electrophile.
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