Tetrahedron Letters p. 4615 - 4618 (1988)
Update date:2022-08-16
Topics:
Bram, Georges
Cabaret, Daniel
Welvart, Zoltan
Geraghty, Niall W. A.
Garwey, James
The stereoselectivity of the alkylation of chiral acetoacetates by racemic secondary alkyl halides changes when the reaction is carried out on a solid support; the change can be interpreted in terms of a model involving surface imposed conformational restrictions.
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