Stereoselective synthesis of 2-aryloxy acids from lactamide derived esters of racemic α-halo carboxylic acids

DOI: 10.1016/0040-4039(96)00391-7

Source and publish data:

Tetrahedron Letters p. 2683 - 2686 (1996)

Update date:2022-08-30

Topics:

Authors:

Devine, Paul N.

Dolling, Ulf -H.

Heid Jr., Richard M.

Tschaen, David M.

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Article abstract of DOI:10.1016/0040-4039(96)00391-7

Pyrrolidine derived (S)-lactamide auxiliaries mediate a highly stereoselective coupling reaction between racemic α-haloacids and aryloxides. These amide auxiliaries exhibit enhanced rates of reaction as well as increased degrees of diastereoselection over

Full text of DOI:10.1016/0040-4039(96)00391-7

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