Highly Efficient Abnormal NHC Ruthenium Catalyst for Oppenauer-Type Oxidation and Transfer Hydrogenation Reactions

Article abstract of DOI:10.1021/acscatal.9b03677

The ruthenium complex [Ru(OAc)(a-PC)₂]Br (3) containing two abnormal NHC ligands is obtained by reaction of Ru(OAc)₂(PPh₃)₂ (1) with 1-(2-diphenylphosphinoethyl)-3-mesitylimidazolium bromide in the presence of NaOAc. Complex 3 catalyzes the Oppenauer-type oxidation of a number of alcohols at unrivalled reaction rates reaching TOFs up to 550 000 h^-1, at low catalyst loadings (S/C higher than 10 000) and using acetone in stoichiometric amounts. Complex 3 is also highly active in the reverse transfer hydrogenation of several ketones with 2-propanol, displaying TOFs up to 600 000 h^-1

Full text of DOI:10.1021/acscatal.9b03677

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Letter
Highly Efficient Abnormal NHC Ruthenium Catalyst for
Oppenauer-type Oxidation and Transfer Hydrogenation Reactions
Lorenz Pardatscher, Benjamin J. Hofmann, Pauline Josephine Fischer,
Sebastian Martin Hölzl, Robert M. Reich, Fritz E. Kühn, and Walter Baratta
ACS Catal., Just Accepted Manuscript • DOI: 10.1021/acscatal.9b03677 • Publication Date (Web): 04 Nov 2019
Downloaded from pubs.acs.org on November 4, 2019
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Highly Efficient Abnormal NHC Ruthenium Catalyst for Oppenauer-type
Oxidation and Transfer Hydrogenation Reactions
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