Highly Regioselective Palladium-Mediated Synthesis of Stereoisomerically Pure (Z)- and (E)-Alkyl 2-Bromo-3-(hetero)arylpropenoates

Article abstract of DOI:10.1016/0040-4039(94)85040-2

Stereoisomerically pure (Z)- and (E)-alkyl 2-bromo-3-(hetero)arylpropenoates, (Z)- and (E)-2, have been efficiently and selectively prepared by Pd(0)-mediated cross-coupling reaction between (hetero)arylzinc halides, 5, and easily available (Z)- and (E)-a