Journal of Polymer Science, Part A: Polymer Chemistry p. 2961 - 2974 (2010)
Update date:2022-08-11
Topics:
Gou, Peng-Fei
Zhu, Wei-Pu
Xu, Ning
Shen, Zhi-Quan
Novel amphiphilic A14B7 multimiktoarm star copolymers composed of 14 poly(ε-caprolactone) (PCL) arms and 7 poly(acrylic acid) (PAA) arms with β-cyclodextrin (β-CD) as core moiety were synthesized by the combination of controlled ring-opening polymerization (CROP) and atom transfer radical polymerization (ATRP). 14-Arm star PCL homopolymers (CDSi-SPCL) were first synthesized by the CROP of CL using per-6-(tert-butyl-dimethylsilyl) -β-CD as the multifunctional initiator in the presence of Sn(Oct) 2 at 125 °C. Subsequently, the hydroxyl end groups of CDSi-SPCL were blocked by acetyl chloride. After desilylation of the tert- butyldimethylsilyl ether groups from the β-CD core, 7 ATRP initiating sites were introduced by treating with 2-bromoisobutyryl bromide, which further initiated ATRP of tertbutyl acrylate (tBA) to prepare well-defined A 14B7 multimiktoarm star copolymers [CDS(PCL-PtBA)]. Their molecular structures and physical properties were in detail characterized by 1H NMR, SEC-MALLS, and DSC. The selective hydrolysis of tert-butyl ester groups of the PtBA block gave the amphiphilic A14B7 multimiktoarm star copolymers [CDS(PCL-PAA)]. These amphiphilic copolymers could self-assemble into multimorphological aggregates in aqueous solution, which were characterized by dynamic light scattering (DLS), transmission electron microscopy (TEM) and atomic force microscopy (AFM).
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