BULLETIN OF THE
Note
KOREAN CHEMICAL SOCIETY
1
.69–1.91 (m, 8H), 1.19–1.33 (m, 5H), 1.09 (t,
J = 7.2 Hz, 6H).
1
Compound 4d: H NMR (300 MHz, CDCl ): δ 8.69 (br,
3
1
H), 8.06 (s, 1H), 7.76 (d, J = 7.8 Hz, 1H), 7.66 (d,
J = 7.8 Hz, 1H), 7.56(d, J = 8.7 Hz, 2H), 7.45 (t,
J = 7.8 Hz, 1H), 6.96 (d, J = 8.7 Hz, 2H), 3.99 (t,
J = 6.6 Hz, 2H), 3.58–3.64 (m, 2H), 2.67–2.77 (m, 6H),
1
6
.76–1.92 (m, 4H), 1.30–1.50 (m, 6H), 1.11 (t, J = 7.2 Hz,
H), 0.91 (t, J = 7.2 Hz, 3H).
1
Compound 4e: H NMR (300 MHz, CDCl ): δ 8.59 (s,
3
1
H), 8.09 (s, 1H), 7.80 (d, J = 7.5 Hz, 1H), 7.67 (d,
J = 7.5 Hz, 1H), 7.56 (d, J = 8.7 Hz, 2H), 7.46 (t,
J = 7.5 Hz, 1H), 6.97 (d, J = 8.7 Hz, 2H), 3.99 (t,
J = 6.3 Hz, 2H), 3.60–3.65 (m, 2H), 2.78–2.85 (m, 4H),
1
.94–2.00 (m, 2H), 1.76–1.85 (m, 2H), 1.25–1.47 (m, 8H),
1
.17 (t, J = 7.2 Hz, 6H), 0.90 (t, J = 6.3 Hz, 3H).
1
Compound 8: H NMR (300 MHz, CDCl ): δ 8.62 (s,
3
1
H), 8.13 (s, 1H), 7.82 (d, J = 8.1 Hz, 1H), 7.67 (d,
J = 8.1 Hz, 1H), 7.45 (t, J = 8.1 Hz, 1H), 7.16–7.19 (m,
2
3
H), 6.95 (d, J = 8.7 Hz, 1H), 4.02–4.11 (m, 4H),
.60–3.66 (m, 2H), 2.82–2.89 (m, 6H), 2.00 (quint,
J = 6.0 Hz, 1H), 1.78–1.87 (m, 4H), 1.49–1.59 (m, 4H),
.20 (t, J = 7.2 Hz, 6H), 0.96–1.01 (m, 6H).
1
Acknowledgment. This work was supported by the
National Research Foundation of Korea (NRF) grant
funded by the Korea government (MSIP) (NRF-
2
015R1A5A1008958)
References
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Figure 2. Inhibitory effect of derivatives on phagocytosis of
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1
2
2
0 μM except cytochalasin D (CTC). (b) Cytotoxicity of all test
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(
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(
(
(
t, J = 6.6 Hz, 2H), 3.59 (q, J = 5.4 Hz, 2H), 2.64–2.74
m, 6H), 1.81–1.87 (m, 3H), 1.70 (q, J = 6.6 Hz, 2H), 1.08
6
. A. Neschadim, L. P. Kotra, D. R. Branch, Autoimmun. Rev.
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t, J = 7.2 Hz, 6H), 0.98 (d, J = 6.6 Hz, 6H).
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1
Compound 4c: H NMR (300 MHz, CDCl ): δ 8.70 (br,
3
1
H), 8.05 (s, 1H), 7.75 (d, J = 7.8 Hz, 1H), 7.65 (d,
2
0, 5262.
J = 7.8 Hz, 1H), 7.55 (d, J = 9 Hz, 2H), 7.44 (t,
J = 7.8 Hz, 1H), 6.96 (d, J = 9 Hz, 2H), 3.79 (d, J = 6 Hz,
8
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S.-Y. Park, K. H. Min, K. W. Hwang, Int. Immunophar-
macol. 2016, 32, 125.
2H), 3.60 (q, J = 5.7 Hz, 2H), 2.65–2.75 (m, 6H),
Bull. Korean Chem. Soc. 2017, Vol. 38, 120–122
© 2016 Korean Chemical Society, Seoul & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
www.bkcs.wiley-vch.de
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