Journal of the American Chemical Society
Communication
excitation are preferable for biological probes. To transcribe shifts
in excitation to shifts in emission, terthiophene 3 was considered
as FRET donor for mechanophore 2 (Figure 1). Donor 3
exhibited a mechanoinsensitive hypsochromic λex = 400 nm in
DOPC and DPPC membranes (Figure 2E, dashed, cyan and
purple). In this region, the excitation of flipper 2 is weak and
mechanoinsensitive (Figure 2E, dotted, blue, red). Flipper 2 will
thus not interfere significantly with the excitation of donor 3
under varied conditions.
Competence in Research (NCCR) Chemical Biology (MGG,
SM, AR), the NCCR Molecular Systems Engineering (SM) and
the Swiss NSF for financial support (MGG, SM, AR, EV). ED is a
fellow of the HFSP.
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ASSOCIATED CONTENT
* Supporting Information
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S
Detailed experimental procedures. This material is available free
AUTHOR INFORMATION
Corresponding Authors
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Loranger, S.; Cicoira, F. J. Mater. Chem. 2010, 20, 669. (d) Kim, O.-K.;
Fort, A.; Barzoukas, M.; Blanchard-Desce, M.; Lehn, J.-M. J. Mater.
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Notes
The authors declare no competing financial interest.
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ACKNOWLEDGMENTS
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We thank Giulio Gasparini, David Alonso Doval, Andrea Fin and
Nicolas Chiaruttini for contributions to synthesis and experi-
ments, the NMR and the Sciences Mass Spectrometry (SMS)
platforms for services, and the University of Geneva, the
European Research Council (ERC Advanced Investigator,
MGG, SM; Starting Investigator, AR), the National Centre of
D
J. Am. Chem. Soc. XXXX, XXX, XXX−XXX