Highly Chemoselective Reduction of N-Boc Protected Lactams

DOI: 10.1016/S0040-4039(00)73047-4

Source and publish data:

Tetrahedron Letters p. 2053 - 2056 (1994)

Update date:2022-08-11

Topics:

Authors:

Pedregal, Concepcion

Ezquerra, Jesus

Escribano, Ana

Carreno, M. Carmen

Ruano, Jose L. Garcia

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Article abstract of DOI:10.1016/S0040-4039(00)73047-4

N-Boc protected lactams can be reduced chemoselectively in the presence of other groups such as esters, nitriles carbamates or double bonds by first reducing the amide carbonyl group into the corresponding hemiaminal using lithium triethylborohydride foll

Full text of DOI:10.1016/S0040-4039(00)73047-4

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