Isolation of neoanisatin derivatives from the pericarps of Illicium majus with other constituents

DOI: 10.1248/cpb.39.1773

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1773 - 1778 (1991)

Update date:2022-08-16

Topics:

Authors:

Kouno Kouno

Hashimoto

Enjoji Enjoji

Takahashi

Kaneto Kaneto

Yang Yang

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Article abstract of DOI:10.1248/cpb.39.1773

Further studies on the constituents of Illicum majus have resulted in the isolation of five new neoanisatin derivatives and two known phytoquinoides together with two known neolignans. Two of the neoanisatin derivatives are 1-hydroxyl, which are the first examples isolated anisatin derivatives so far. Another one, 2-oxoneoanisatin, exhibited picrotoxin-like convulsions in mice, the same as anisatin. The other two 3,4-dehydro-2-oxoneoanisatin isomers could not be separated from each other, even with high performance liquid chromatography.

Full text of DOI:10.1248/cpb.39.1773

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