An enzymatic enantioselective route to methyl carboxylate 2,3-methanohomoserine γ-lactone; a precursor of chiral 2,3-methanohomoserine

Article abstract of DOI:10.1080/00397919108016415

Enzymatic hydrolysis of Dimethyl 2 - (tetrahydropyranyl) hydroxymethyl cyclopropane 1,1 - dicarboxylate 6 with an industrial esterase, followed by a deprotection of tetrahydropyranyl ether affords the title compound in 20% yield.

Full text of DOI:10.1080/00397919108016415

Synthetic Communications
ISSN: 0039-7911 (Print) 1532-2432 (Online) Journal homepage: http://www.tandfonline.com/loi/lsyc20
An Enzymatic Enantioselective Route to Methyl
Carboxylate 2,3 - Methanohomoserine γ-Lactone; A
Precursor of Chiral 2,3 - Methanohomoserine
Cécile Fliche , Jacques Braun & François Le Goffic
To cite this article: Cécile Fliche , Jacques Braun & François Le Goffic (1991) An Enzymatic
Enantioselective Route to Methyl Carboxylate 2,3 - Methanohomoserine γ-Lactone; A Precursor
of Chiral 2,3 - Methanohomoserine, Synthetic Communications, 21:14, 1429-1432, DOI:
10.1080/00397919108016415
To link to this article: http://dx.doi.org/10.1080/00397919108016415
Published online: 24 Sep 2006.
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Date: 21 June 2016, At: 18:08