Tetrahedron Asymmetry p. 1767 - 1770 (2009)
Update date:2022-08-17
Topics:
Panchgalle, Sharad P.
Gore, Rohitkumar G.
Chavan, Subhash P.
Kalkote, Uttam R.
An efficient enantioselective synthesis of β-adrenergic blockers (S)-propranolol and (S)-naftopidil with >98% ee using an l-proline-catalyzed α-aminoxylation of an aldehyde as a key step is described.
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