Stereospecific synthesis of tetrasubstituted Z-enol silyl ethers by a three component coupling process

Article abstract of DOI:10.1016/S0040-4039(97)01293-8

The coupling of an acylsilane, 2-propenyllithium and an alkyl halide produces tetrasubstituted Z-enol silyl ether in good yields, and provides the first route to these isomerically pure compounds.