11076
A. K. Sinha et al. / Tetrahedron 63 (2007) 11070–11077
(
(
1
1
2H, m), 7.08 (1H, d, J 17.0 Hz), 6.95 (1H, d, J 8.2 Hz), 5.74
1H, s), 3.91 (3H, s); d (75.4 MHz, CDCl ) 146.8, 145.8,
D.; Featherbe, L.; Kurtz, D. Diabetes 1987, 36, 632–640; (c)
Manickam, M.; Ramanathan, M.; Jahromi, M. A. F.;
Chansouria, J. P. N.; Ray, A. B. J. Nat. Prod. 1997, 60, 609–
610; (d) Pezet, R. FEMS Microbiol. Lett. 1998, 167, 203–
208; (e) Rimando, A. M.; Cuendet, M.; Desmarchelier, C.;
Mehta, R. G.; Pezzuto, J. M.; Duke, S. O. J. Agric. Food
Chem. 2002, 50, 3453–3457.
C
3
35.3, 133.8, 131.7, 131.4, 128.7, 127.8, 126.0, 125.8,
23.8, 123.6, 123.0, 120.6, 114.7, 108.6 and 56.0. HREIMS
+
data: m/z [M+H] for C H O , calculated¼277.3440; ob-
1
9 17 2
served¼277.3441.
0
White solid (mp 131–134 C; lit.
4
1
1
6
(
1
1
.4.14. 3,4,4 -Trimethoxystilbene (Table 2/16b and
7b).
7. (a) Hatanaka, T.; Fujita, K.; Ohsumi, K.; Nakagawa, R.;
Fukuda, Y.; Nihei, Y.; Suga, Y.; Akiyama, Y.; Tsuji, T. Bioorg.
Med. Chem. Lett. 1998, 8, 3371–3374; (b) Pettit, G. R.;
Grealish, M. P.; Jung, M. K.; Hamel, E.; Pettit, R. K.;
Chapuis, J. C.; Schmidt, J. M. J. Med. Chem. 2002, 45, 2534–
2542; (c) Kim, S.; Ko, H.; Park, J. E.; Jung, S.; Lee, S. K.;
Chun, Y.-J. J. Med. Chem. 2002, 45, 160–164; (d) Aslam,
S. N.; Stevenson, P. C.; Phythian, S. J.; Veitch, N. C.; Hall,
D. R. Tetrahedron 2006, 62, 4214–4226; (e) Li, W.; Li, H.; Li,
Y.; Hou, Z. A. Angew. Chem., Int. Ed. 2006, 45, 7609–7611.
2
4f
ꢀ
35 C); d (300 MHz, CDCl ) 7.38 (2H, d, J 8.5 Hz),
24f
mp 133–
ꢀ
.98–6.92 (2H, m), 6.86–6.76 (5H, m), 3.88 (3H, s), 3.83
H
3
3H, s), 3.76 (3H, s); d (75.4 MHz, CDCl ) 159.1, 149.1,
C 3
48.6, 130.8, 130.3, 127.4, 126.4, 119.5, 114.1, 111.3,
08.6, 55.9, 55.8 and 55.3.
Acknowledgements
8
. (a) Dey, B. B.; Row, K. K. J. Indian Chem. Soc. 1925, 1, 277–
287; (b) Gusten, H.; Salzwedel, M. Tetrahedron 1967, 23, 173–
185; (c) Belucci, G.; Chiappe, C.; Moro, G. L. Tetrahedron
Lett. 1996, 37, 4225–4228; (d) Myers, A. G.; Tanaka, D.;
Mannion, M. J. Am. Chem. Soc. 2002, 124, 11250–11251; (e)
Wang, J.-X.; Fu, Y.; Hu, Y. Angew. Chem., Int. Ed. 2003, 41,
Two of us (V.K. and A.S.) are indebted to UGC and CSIR
Delhi, respectively, for the award of SRF. The authors grate-
fully acknowledge the Director of I.H.B.T., Palampur for his
kind cooperation and encouragement.
2757–2760; (f) Cella, R.; Stefani, H. A. Tetrahedron 2006,
62, 5656–5662.
Supplementary data
9
. (a) Gaukroger, K.; Hadfield, J. A.; Hepworth, L. A.; Lawrwnce,
N. J.; McGown, A. T. J. Org. Chem. 2001, 66, 8135–8138; (b)
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1
0. Sp €a th, E.; Kromp, K. Chem. Ber. 1941, 74, 189–192.
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