OXIDATIVE TRAPPING OF TRANSIENT THIAZOLIUM-ALDEHYDE ADDUCTS BY INTRAMOLECULAR FLAVIN. FLAVIN-THIAMINE BISCOENZYME MODEL

Article abstract of DOI:10.1246/cl.1981.961

A biscoenzime which has within a molecular structure both flavin and thiazolium ion was synthesized.In the presence of the biscoenzyme and hexadecyltrimethylammonium bromide (CTAB) micelle, aldehydes were efficiently converted to carboxylic acids and the acyloin condensation products were scarcely detected. Thus, the biscoenzyme serves as an interesting model system for pyruvate dehydrogenase.