Stereoselective one-pot synthesis of β-lactams by reaction of 2-pyridylthioesters with imines in the presence of AlBr3 or EtAlCl2

DOI: 10.1016/0040-4020(95)01087-4

Source and publish data:

Tetrahedron p. 2583 - 2590 (1996)

Update date:2022-08-11

Topics:

Authors:

Annunziata, Rita

Benaglia, Maurizio

Cinquini, Mauro

Cozzi, Franco

Martini, Oscar

Molteni, Valentina

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Article abstract of DOI:10.1016/0040-4020(95)01087-4

The reactions of some 2-pyridylthioesters with imines in the presence of AlBr₃ or EtAlCl₂ and of a tertiary amine afford β-lactams in a simple one-pot procedure with fair to high trans stereoselectivity. The condensation can be also

Full text of DOI:10.1016/0040-4020(95)01087-4

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