Synthesis of dihydro-2,3-furandiones from diethyl oxalate and aldehydes through the action of sodium methoxide

Article abstract of DOI:10.1055/s-1991-26447

Dihydro-4,4-dimethyl-2,3-furandione (4e) was synthesized from diethyl oxalate, methylpropanal (1a) and formaldehyde in the presence of sodium methoxide. In a similar manner, analogs of dihydro-2,3-furandione 4 were prepared using other aldehydes.