REACTION OF 2-AMINO-2-DEOXY-D-GLUCOSE AND LYSINE: ISOLATION AND CHARACTERIZATION OF 2,5-BIS(TETRAHYDROXYBUTYL)PYRAZINE

Article abstract of DOI:10.1016/0008-6215(88)80006-5

The reaction of 2-amino-2-deoxy-D-glucose with lysine in water under simulated physiological conditions gave several browning products, with characteristic optical (λ_max 340 nm) and fluorescent properties (emission at 430 nm for excitation at 362 nm).The major product was isolated and characterized by mass spectrometry and n.m.r. spectroscopy as 2,5-bis(tetrahydroxybutyl)pyrazine derived by the condensation of two molecules of 2-amino-2-deoxy-D-glucose.