Chinese Chemical Letters p. 161 - 164 (2012)
Update date:2022-08-10
Topics:
Nandre, Kamalakar P.
Salunke, Jagdish K.
Nandre, Jitendra P.
Patil, Vijay S.
Borse, Amul U.
Bhosale, Sidhanath V.
We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).
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