Synthesis of optically active 4-hydroxymandelic acid and derivatives via regio- and stereoselective Friedel-Crafts alkylation

DOI: 10.1016/S0957-4166(00)82212-0

Source and publish data:

Tetrahedron Asymmetry p. 2411 - 2414 (1993)

Update date:2022-08-11

Topics:

Authors:

Bigi Bigi

Sartori Sartori

Maggi Maggi

Cantarelli

Galaverna

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(00)82212-0

Optically active 4-hydroxymandelic esters were prepared in good yields and very high diastereoselectivity (up to 96% d.e.) via para-hydroxyalkylation of phenolic ethers. Enantiomeric pure 4-hydroxymandelic acid is available by hydrolysis.

Full text of DOI:10.1016/S0957-4166(00)82212-0

Products guided by the article

Product name:(S)-4-hydroxymandelic acid

Cas No:13244-75-2

R&D Labs maybe for 13244-75-2

Liaoning Yufeng Chemical Co.,Ltd.

Contact:86-0419-3418888

Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
Chemtrade International ( China )

Contact:+86-532-86893005

Address:Rm 2-501, Huaxia Zonghe Building, No. 410 JInggangshan Road, Huangdao
Shanghai He Yang International Trading Co., Ltd.

Contact:+86-21-52043598

Address:Room 816, Blag.5, No.58 Huachi Road
Zha Yan

Contact:+86-13914766747

Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
Wuhan Better Organic Technology Inc.

Contact:13307163183

Address:Wuhan Economic&Technology Development Zone, Hubei

Relevant to this article

Doi:10.1016/0304-4165(71)90210-8
(1971)
Kinetics of metal exchange between cadmium mesoporphyrin and zinc and cobalt salts in organic solvents

Doi:10.1023/B:RUCO.0000022806.85114.93
(2004)
Dichloroborane-dioxane: An exceptional reagent for the preparation of alkenyl- and alkylboronic acids

Doi:10.1016/j.tetlet.2003.08.086
(2003)
Acetamidine-palladium complex immobilized on γ-Fe₂O₃ nanoparticles: A novel magnetically separable catalyst for Heck and Suzuki coupling reactions

Doi:10.1039/c4ra04830j
(2014)
Synthesis of heterocycle-linked [60] fullerene derivatives by heterocyclic o-quinodimethane Diels-Alder reaction and self-sensitized photooxygenation of the cycloadducts

Doi:10.1016/S0040-4020(97)00600-5
(1997)
Identification of 2,3-dihydro-gamma-ionylideneethanol in Cercospora cruenta.

Doi:10.1271/bbb.65.810
(2001)

Article Doi