
Tetrahedron Asymmetry p. 2411 - 2414 (1993)
Update date:2022-08-11
Topics:
Bigi
Sartori
Maggi
Cantarelli
Galaverna
Optically active 4-hydroxymandelic esters were prepared in good yields and very high diastereoselectivity (up to 96% d.e.) via para-hydroxyalkylation of phenolic ethers. Enantiomeric pure 4-hydroxymandelic acid is available by hydrolysis.
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