RESEARCH ON THE CHEMISTRY OF 2-HETARYLBENZIMIDAZOLES. 2. SYNTHESIS AND PROPERTIES OF 1-METHYL-2-(1'-METHYL-2'-PYRROLYL)BENZIMIDAZOLE

Article abstract of DOI:10.1007/BF00475394

The condensation of 1-methyl-2-formylpyrrole with o-phenylenediamine gave 2-(1'-methyl-2'-pyrrolyl)benzimidazole, which was subjected to methylation.The alkylation product was subjected to electrophilic substitution.The substituent is incorporated in the 4 or 5 position of the hetaryl ring; however, bromination of 1-methyl-2-(1'-methyl-2'-pyrrolyl)benzimidazole leads to the formation of the mono-, di-, and tribromo derivatives, depending on the conditions.The acidophobic properties of the pyrrole ring are partially lost as a consequence of the effect of the benzimidazole ring.