An efficient route to S-N-(9-fluorenylmethoxycarbonyl)-4′-(1-azi-2,2,2-trifluoroethyl) phenylalanine

DOI: 10.1016/S0040-4039(00)60743-8

Source and publish data:

Tetrahedron Letters p. 4611 - 4614 (1994)

Update date:2022-08-05

Topics:

Authors:

Fishwick, Colin W. G.

Sanderson, John M.

Findlay, John B. C.

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Article abstract of DOI:10.1016/S0040-4039(00)60743-8

An extremely efficient synthesis of optically pure photoactivatable phenylalanine derivative 1 is described. The key step involves a highly diastereoselective alkylation of a chiral glycine equivalent.

Full text of DOI:10.1016/S0040-4039(00)60743-8

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