Studies directed toward the design of chiral acylating agents. the utility of chiral N-benzoylimides in enantioselective alcohol acylation

Article abstract of DOI:10.1016/S0040-4039(00)73882-2

N-benzoyl-4(5)-tert-butyl-2-oxazolidinone (1b) is found to be an efficient enantioselective acylating agent for aryl n-alkyl carbinols. Selective benzoylation of racemic aryl n-alkyl carbinols with kinetic selectivities of 20-30:1 for the (R) enantiomer i