Reductive lithiation of a trimethyl benzo-1,3-thiazoline: Generation of an α-amino tertiary carbanion and reactions with electrophiles

DOI: 10.1016/0040-4039(95)00753-Y

Source and publish data:

Tetrahedron Letters p. 4463 - 4466 (1995)

Update date:2022-08-16

Topics:

Authors:

Florio Florio

Florio, Saverlo

Capriati

Capriati, Vito

Gallo Gallo

Gallo, Antonio

Cohen Cohen

Cohen, Theodore

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Article abstract of DOI:10.1016/0040-4039(95)00753-Y

Trimethylbenzothiazoline 1 has been reductively lithiated by lithium 4,4'-di-t-butylbiphenylide (LDBB) leading to dianion 3, that has been trapped with electrophiles to give aminodisulfides 4, aminosulfide 8 and aminoalcohols 9.

Full text of DOI:10.1016/0040-4039(95)00753-Y

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