Solvent Influence on Trifluoromethylation Reactions with Cd(CF3)2: One-pot Synthesis of Trifluoromethyl Iron Complexes

DOI: 10.1039/DT9890000739

Source and publish data:

Journal of the Chemical Society, Dalton Transactions p. 739 - 744 (1989)

Update date:2022-08-17

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Authors:

Dukat, Wolfgang

Naumann, Dieter

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Article abstract of DOI:10.1039/DT9890000739

Bis(trifluoromethyl)cadmium complexes Cd(CF3)2*L (L=2CH3CN or CH3OCH2CH2OCH3) react as perfluoroalkyl Grignard reagents with carbonyl-iron halides in a one-pot reaction to yield Fe-CF3 compounds easily.A strong solvent influence is observed.The dependence of the direction of the reactions, either as a trifluoromethylation or a fluorination, is discussed.In the presence of CH3CN a ligand-exchange reaction is observed, yielding trifluoromethyl iron acetonitrile complexes, while carbonyl complexes are obtained in ethers.The compound has been prepared in 65percent yield, and its (19)F n.m.r., i.r., Raman, mass, and Moessbauer spectra recorded.The adventage of observing the (13)C satellites in the (19)F n.m.r. spectra for the analysis of trifluoromethyl metal compounds is established.If the appropriate reaction conditions are used, Cd(CF3)2 complexes react as fluorination reagents and CF2 sources.Thus, on reaction of the trifluoromethyl cadmium reagents with tetracarbonyliron halides in CH3CN, diamagnetic fluoroiron acetonitrile complexes are formed.